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Complex cyanotic heart defects usually need treatment with medicines more often than acyanotic heart defects.
---- Acyanotic heart defect have normal levels of oxyhemoglobin saturation in systemic circulation.
Acyanotic heart defects do not usually cause cyanosis-a bluish tint to the skin, lips, and nail beds due to reduced oxygen flow.
Some complex acyanotic heart defects and many cyanotic heart defects require ongoing treatment with medicines even after the defect is repaired.
VSD is an acyanotic congenital heart defect, aka a Left-to-right shunt, so there are no signs of cyanosis.
If cyanosis develops in a person with acyanotic heart defects, it is generally a result of increased activity (such as crying and feeding) during which more oxygen is needed.
Acyanotic heart defects are heart problems that develop before or at birth but do not normally interfere with the amount of oxygen or blood that reaches the body's tissues.
Acyanotic heart defects without shunting include pulmonary stenosis, a narrowing of the pulmonary valve, aortic stenosis and coarctation of the aorta.
A number of congenital heart defects can cause Eisenmenger syndrome, including atrial septal defects, ventricular septal defects, patent ductus arteriosus, and more complex types of acyanotic heart disease.
Levo-Transposition of the great arteries is an acyanotic heart defect in which the primary arteries are transposed, with the aorta anterior and to the left of the pulmonary artery, and the morphological left and right ventricles are also transposed.
For example, for NT-proBNP, a lower cut-off value is used in distinguishing healthy babies from those with acyanotic heart disease, compared to the cut-off value used in distinguishing healthy babies from those with congenital nonspherocytic anemia.
In screening for congenital heart disease in pediatric patients, an NT-proBNP cut-off value of 91 pg/mL could differentiate an acyanotic heart disease (ACNHD) patient from a healthy patient with a sensitivity of 84% and specificity of 42%.