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Risk factors for amebic liver abscess include:
Blockade of caspases inhibits amebic liver abscess formation in a mouse model of disease.
For amebic liver abscess:
Amebic liver abscess is a collection of pus in the liver in response to an intestinal parasite.
Amebic liver abscess is caused by Entamoeba histolytica, the same parasite that causes amebiasis, an intestinal infection that is also called amebic dysentery.
Expression of amoebapores is required for full expression of Entamoeba histolytica virulence in amebic liver abscess, but is not necessary for the induction of inflammation or tissue damage in amebic colitis.
The total dose in amoebic liver abscess should not exceed 650 mg.
Till today, emetine remains one of the best drugs for treating amoebic liver abscess.
Retinopathy does not occur with the usual dosage for amoebic liver abscess.
Amoebic liver abscess due to Entamoeba histolytica accounts for 10% of cases.
His work on amoebic liver abscess was published in American Journal of Surgery.
A 1979 study of 27 patients treated with dehydroemetine and various other drugs suggested all drug combinations were successful at treating amoebic liver abscesses.
This nitroimidazole compound, like metronidazole, has shown a marked therapeutic response in amoebic liver abscess.
A amoebic liver abscess is a type of liver abscess caused by amebiasis.
Anchovy-paste (or 'chocolate sauce'): Ruptured amoebic liver abscess.
In patients having myocardial disease or marked hypertension, emetine can be used for amoebic liver abscess, as the benefits from it may outweigh possible hazards.
Chloroquine given alone is a safer drug than emetine in amoebic liver abscess, but unfortunately the relapse rate is almost 25%.
In 1921, John used quinine hydrochloride, an alkaloid of cinchona in the treatment of amoebic liver abscess.
Intravenous metronidazole is a drug of choice for anaerobic infections Therefore it may be of extra advantage, if used in amoebic liver abscess.
A single oral dose of 2.5 G. metronidazole combined with closed aspiration has also produced dramatic response and cure in patients with amoebic liver abscess.
If the parasite reaches the bloodstream it can spread through the body, most frequently ending up in the liver where it causes amoebic liver abscesses.
Studies by Lazarachick et a revealed presence of anaerobic bacteroides in as many as 26% cases of amoebic liver abscess with so called 'sterile' pus.
Zuberi and Ibrahim found tinidazole to be effective in 86.7% cases of intestinal amoebiasis and in 100% cases of amoebic liver abscess.
The high concentration in the liver parenchyma and the lung allows the drug to act upon E. Histolytica in cases of amoebic liver abscess and pleuropulmonary amoebiasis.
'Entamoeba histolytica' is the pathogen responsible for 'amoebiasis' (which includes amoebic dysentery and amoebic liver abscesses), while others such as 'Entamoeba coli' and 'Entamoeba dispar' are harmless.
Metronidazole should not be used as a single agent for the eradication of bowel infection.33 When used alone, a few cases are known to have developed amoebic liver abscess, months after apparently successful cure of dysentery.
Studies showed that because of very high concentration in the liver extremely small amounts of the drug were effective in amoebic liver abscess, but with such low doses, eradication of amoebae in the bowel was uncertain.
Its greater concentration and duration of action in the liver as compared to that in the intestinal wall explains its high efficacy in amoebic liver abscess and also its low parasitic cure rate for intestinal amoebiasis.