cotransport

This is possible because cholera does not interfere with sodium-glucose cotransport.

One proposed mechanism for this phenomenon is a glucose-dependent cotransport of fructose.

Crane's discovery of cotransport led directly to the development of oral rehydration therapy.

Crane's discovery of cotransport was the first ever proposal of flux coupling in biology.

Instead, the protein is responsible for the cotransport of sodium ions and ergothioneine, which is an antioxidant, into cells.

Ethacrynic acid acts by inhibiting sodium-potassium-chloride cotransport in the ascending loop of Henle.

The transport of norepinephrine back into presynaptic cell is made possible by the cotransport with Na and Cl.

For example, some transporters use energy obtained by the cotransport, or symport, of Na in order to move glutamate across membranes.

Robert K. Crane, Class of 1942, American biochemist, discoverer of sodium-glucose cotransport.

Cotransport of ions by symporters and antiporter carriers is commonly used to actively move ions across biological membranes.

Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation.

In the early 1960s, biochemist Robert K. Crane discovered the sodium-glucose cotransport as the mechanism for intestinal glucose absorption.

Such neurotransporter cotransport systems are highly diverse, as recent development indicates that uptake systems are generally selective and associate with a specific neurotransmitter.

NBCs are also responsible for electrogenic transepithelial bicarbonate cotransport in kidney proximal tubules [ 4, 5].

These size fractions were then sequentially injected into Xenopus oocytes to ultimately find the RNA species that induced the expression of sodium-glucose cotransport.

This process, called active transport, get its energy from ATP and other ATP-related cotransport systems that produce energy, like the sodium-potassium pump.

In August 1960, in Prague, Crane presented for the first time his discovery of the sodium-glucose cotransport as the mechanism for intestinal glucose absorption.

The latter couple glutamate and aspartate uptake to the cotransport of Na and the counter-transport of K, with no apparent dependence on Cl.

However, glucose, amino acids, inorganic phosphate, and some other solutes are reabsorbed via secondary active transport through cotransport channels driven by the sodium gradient out of the nephron.

Finally, of course, there must be a substance such as glucose, which can activate the sodium cotransport systems in the gut epithelium - the systems upon which the principle of ORT relies.

Similar discrepancies between measurements of solute uptake with brush border membrane vesicles or tissue biopsies and in vivo experiments have been observed in studies examining sodium/glucose cotransport in cystic fibrosis.

As the cotransport of glucose with sodium from the lumen does not directly require ATP hydrolysis but depends upon the action of the ATPase, this is described as secondary active transport.

GLAST mediates the transport of glutamic and aspartic acid with the cotransport of three Na and one H cations and counter transport of one K cation.

Although solute dependent sodium absorption via the cotransport mechanism is of major therapeutic importance during diarrhoeal states, sodium is mainly absorbed from the jejunum through other passive processes such as electroneutral sodium chloride absorption and solvent drag.

The success of complex carbohydrate containing ORS in clinical studies may be more closely related therefore to their very low osmolality relative to standard hypertonic monomer ORS than to the kinetic advantage factor or the increased substrate availability for glucose/sodium cotransport.