cytoprotection

Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents.

Thus, indomethacin treatment suppressed both adaptive cytoprotection and the difference between dietary groups.

Protocol 3 studied the effects of indomethacin pretreatment on adaptive cytoprotection in the three experimental groups.

In contrast, when comparing the adaptive cytoprotection curves (Fig 5), the difference between diet groups is evident and significant (p<0.05).

All groups exhibited higher damage scores than those observed in the adaptive cytoprotection experiments shown in Figure 5 (p<0.05).

The main function of Hsp27 is to provide thermotolerance in vivo, cytoprotection, and support of cell survival under stress conditions.

The importance of phospholipid adherence to the mucosal surface in gastric cytoprotection was first reported by Lichtenberger et al.

However, the exact role of this protein in intracellular transport of bile acids and cytoprotection was undefined.

Studies have shown that the BVR redox cycle is essential in providing physiological cytoprotection.

The cytoprotective mechanism of this barrier is not yet completely understood, although surface active phospholipids have been reported to play a key role in gastric cytoprotection.

In conclusion, dietary polyunsaturated fatty acids enhance duodenal resistance to acid by potentiation of adaptive cytoprotection.

Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection.

This is because the unifying principle is cytoprotection of the renal tubular cells which, if lethally injured, may only be 'rescued' for a short time.

Hence, we postulated that adaptive cytoprotection maintains a physiological equilibrium between duodenal mucosal resistance and luminal acidity.

Other investigators claim that endogenous prostaglandins may not be essential since gastric cytoprotection persists after pretreatment with prostaglandin synthesis inhibitors.

Protocol 2 studied the phenomenon of adaptive cytoprotection in response to mild irritation of the duodenal mucosa in the three experimental groups.

In summary, our study shows that adaptive cytoprotection of the duodenal mucosa to luminal acid can be modulated by the dietary intake of fat.

Diets rich in polyunsaturated fatty acids enhance the phenomenon of adaptive cytoprotection and render the duodenal mucosa more resistant to acid.

In contrast, in IEC-18 cells all three antioxidants produced similar degrees of cytoprotection, limiting peroxynitrite-induced apoptosis (Table 1).

A second series of experiments tested the mucosal resistance to acid after pretreatment with a mild dose of acid to induce adaptive cytoprotection.

A bark extract was reported to reduce formation of stomach ulcers in mice under several stresses, due to cytoprotection and reduced secretion of stomach acid.

The Gla domain is particularly useful for binding to negatively charged phospholipids for anticoagulation and to EPCR for cytoprotection.

The cytoprotection afforded by schisandrin B against Aβ -induced toxicity in rat cortical neurons involves a mitochondria-mediated signaling pathway and an antioxidant response.

Thus, in regard to stress or injury, the function of adenosine is primarily that of cytoprotection preventing tissue damage during instances of hypoxia, ischemia, and seizure activity.

In experimental models of gastric damage, there is evidence that the ability of the gastric mucosa to synthesise prostaglandins plays an important part in mediating adaptive cytoprotection.