deleterious mutation

Of 127 participants, 22 were found to have deleterious mutations.

They would still have a tremendous number of deleterious mutations, and a few positive.

Deleterious mutation: The change is proven to cause significant risks.

Now, suppose that deleterious mutations reduce survival below this optimal value.

It is nevertheless possible for a deleterious mutation to be spread throughout a population through the effect of genetic drift.

Since the family has a documented deleterious mutation, standard of care recommendations include guidelines for screening and monitoring.

It is highly unlikely, however, that the same deleterious mutations will be prevalent in both populations after a long period of separation.

Here the techniques to reduce inbreeding also help decrease the accumulation of deleterious mutations.

We do seem to have beaten one major problem: we've developed plants that purge themselves of deleterious mutations due to radiation.

More individuals survive to later ages, so the force of selection against late-acting deleterious mutations is stronger.

Three of the men with deleterious mutations had no family history of prostate, breast, or ovarian cancer.

Whether the variant has been documented in the presence of a documented deleterious mutation.

Identification as the carrier of a deleterious mutation may affect self-esteem, family relationships, and quality of life.

This increases the damage done by recessive deleterious mutations, in a process known as inbreeding depression.

Deleterious mutations in these genes can impact normal intellectual and emotional functioning in humans.

Deleterious mutations that arise from inbreeding can be removed by purging, or natural selection.

Antagonistic coevolution with parasites increases the cost of host deleterious mutations.

A deleterious mutation has a negative effect on the phenotype, and thus decreases the fitness of the organism.

Suppose now that deleterious mutations are age-specific.

Senescence of clones is probably caused by the accumulation of deleterious mutations.

Families with a documented deleterious mutation.

This overall fitness decrease of a species is caused by an accumulation of deleterious mutations throughout the population.

Without sexual selection, an unattractive individual might find a superior mate with few deleterious mutations, and have healthy children that are likely to survive.

Therefore, late-acting deleterious mutations could accumulate in populations over evolutionary time through genetic drift.