dermal papilla

Stem cells and dermal papilla cells have been discovered in hair follicles.

Specifically BMP4 is found in the dermal papilla.

Those cells then chemically interact with the dermal papilla, an operation that promotes cell division and maturation.

Breeding males also develop - somewhat hair-like - dermal papillae that extend along the flanks and thighs.

All reptilian scales have a dermal papilla underlying the epidermal part, and it is there that the osteoderms, if present, would be formed.

Low energy radiofrequency irradiation induces IGF-1 in cultured human dermal papilla cells.

In vitro studies have shown dermal papilla cells derived from human hair follicles spontaneously produce nitric oxide.

Several lines of evidence support the dermal papilla of the hair follicle as the androgenic target for hair loss prevention and reversal.

Testosterone is converted (within the cells of the hair follicle's dermal papilla) by 5-alpha reductase to DHT.

The male hairy frog (Trichobatrachus robustus) has dermal papillae projecting from its lower back and thighs giving it a bristly appearance.

IGF-1 is modulated by IGF binding protein, which is produced in the dermal papilla.

Latanoprost (Xalatan ) has shown ability to promote scalp hair density and pigmentation, and is theorized to function at the dermal papilla.

Oedematous dermal papillae are typically seen with increased vascularity and a mixed inflammatory infiltrate including lymphocytes, plasma cells and neutrophils.

Mouse models have found valproic acid activates alkaline phosphatase in human dermal papilla cells and induces hair regeneration in transgenic mice.

Basal nitric oxide levels are enhanced threefold by stimulating dermal papilla cells with 5alpha-dihydrotestosterone (DHT) but not with testosterone.

Pin feathers begin to develop after the feather bud invaginates a cylinder of epidermal tissue around the base of the dermal papilla, forming the feather follicle.

To form a new hair, the dermal papilla releases a signal that cues the stem cells in the bulge to migrate toward the dermal papilla.

The probe is inserted to the depth of the dermal papilla or hair matrix, which is the site of formation of hair from highly mitotic and keratinized cells.

The factors seem to work in synergistic fashion: when two or three are present in the blood supply surrounding a follicle, together they seem to activate the dermal papilla cells into a growth phase.

Whiskers Sprout From Ear Only very recently have scientists learned to manipulate the dermal papilla cells with any deftness, and in so doing they are learning how vital the cells are to hair growth.

A number of herbals substance have been reported to inhibit 5 alpha reductase, the enzyme which catalyzes conversion of testosterone to DHT to cause androgenic miniaturization at the hair follicle dermal papilla.

The researchers also demonstrated that they could take dermal papilla cells from the coat of a mouse and inject them into the skin of the mouse's paw pad, which normally is as hair-free as the palm of the human hand.

Seeking to understand which hormones and other chemical signals in the body tweak the dermal papilla into action, some researchers are scrutinizing the surface of the cells for telltale receptors, the proteins that allow cells to communicate with the outside world.

Direct vasodilation of hair follicle arteries and increasing blood flow to dermal papilla by opening Kir 6.0 potassium channel pores coupled with SURs on plasma membranes of smooth muscle cells, mimicking nitric oxide.

DKK1 is one of the most upregulated genes in androgen potentiated balding, with DKK-1 messenger RNA upregulated a few hours after DHT treatment of hair follicles at the dermal papilla in vitro.