hemizygous

Males are normally hemizygous for the X chromosome, having only one copy.

Overall incidence of hemizygous males and carrier females is estimated at 1:16,800.

Male hemizygous mutants had an increased susceptibility to bacterial infection.

This permitted a comparison of hemizygous male and homozygous female 3-repeat vs. 4-repeat classes only.

In a more extreme example, male honeybees (known as drones) are completely hemizygous organisms.

Hemophilia is much more common in males than females because males are hemizygous.

A chromosome in a diploid organism is hemizygous when only one copy is present.

The remaining tests were therefore carried out on heterozygous mutant females and hemizygous males.

Males however have only one copy of each X chromosome gene locus, and are described as hemizygous for these genes.

Unless otherwise noted, cells and samples were obtained from animals hemizygous for both transgenes.

Hemizygous males were infertile and thus it was not possible to produce homozygous mutant female mice.

If the conditions are so that the individual is hemizygous or homozygous for the csd gene, they will develop into males.

NPM1 is haploinsufficient in hemizygous mice that are vulnerable to tumor development.

Defective testicular development and XY feminization occur when this gene is hemizygous.

Males with an ABCD1 mutation are hemizygous, as they only have a single X chromosome.

According to this model, if an individual is heterozygous for a certain locus, it develops into a female, whereas hemizygous and homozygous individuals develop into males.

Hemizygous and nullizygous genotypes do not contain enough alleles to allow for comparison of sources, so this classification is irrelevant for them.

The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA.

The condition affects hemizygous males (i.e. all males), as well as homozygous, and in many cases heterozygous females.

Another mutation is a hemizygous deletion in the NLGN4 gene encompassing exons 4, 5, and 6.

Similarly, deletions of 13q14 in low-grade B-cell tumours may be associated with hemizygous or homozygous loss of the retinoblastoma gene.

XY humans hemizygous for the chromosome 9p, where DMRT1 is located, are often feminized.

If one allele is missing, it is hemizygous, and, if both alleles are missing, it is nullizygous.

However, the 10% rate was obtained with hemizygous p53-deficient mice, the counterpart of humans with the Li-Fraumeni syndrome, and rates near 1% were more typical.

Subsequently, the rate of phenotypic reversion from trans-silencing was observed for hemizygous and homozygous lineages of E82 and L91.