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This was found secondary to hypotonia in some children with 1p36.
It may cause hypotonia in the newborn if given closely before delivery.
The condition was first reported in a single infant presenting with persistent hypotonia.
For instance, some people with hypotonia may experience constipation, while others have no bowel problems.
Hypotonia and/or hypertonia are present in nearly all individuals with tetrasomy 18p.
The associated hypotonia may start prenatally or after birth.
When used in pregnancy, it might cause hypotonia.
The most constant features seen are developmental delay, hypotonia, and mental retardation.
Muscular disease, including hypotonia and cardiomyopathy, usually occurs later.
Both have symptoms of hypotonia and retarded development.
The outcome in any particular case of hypotonia depends largely on the nature of the underlying disease.
Often, hyperkinesia is paired with hypotonia, a decrease in muscle tone.
Some of these individuals have hypotonia and tremors.
Newborns may present with profound hypotonia (low muscle tone), and a poor ability to feed.
Muscles are usually underdeveloped and lack normal tone (hypotonia).
A minority may also have hypotonia or hypertonia even as early as the newborn period.
Moreover, hypotonia is greatest during this period, even though muscle tone increases with age, it never reaches normal levels.
If the cause of the hypotonia is thought to lie in the brain, then it might be classified as a cerebral palsy.
Neurological symptoms, such as developmental decline, hypotonia, and mental retardation have also been reported.
Little is known about children with Down syndrome but commonly hypotonia or poor muscle mass is to blame.
Affected neonates may demonstrate nonspecific signs of poor feeding and hypotonia.
The initial hypotonia may progress to hypertonia with spasticity.
At that time the hypotonia and delayed development were not considered to be suggestive of a neurotransmitter defect.
Death is usually due to renal failure or complications from hypotonia, in the first or second decade of life.
Significant findings on her physical exam included a distended abdomen with hepatomegaly and hypotonia.