oncocytoma

An oncocytoma is a tumor made up of oncocytes, a special kind of cell.

Oncocytoma can arise in a number of organs.

Renal oncocytoma is considered benign, cured by nephrectomy.

The differential diagnosis includes sebaceous lymphadenoma and oncocytoma.

Renal oncocytoma, a kidney tumour composed of oncocytes.

Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.

The salivary gland oncocytoma is a well-circumscribed, benign neoplastic growth also called an oxyphilic adenoma.

An oncocytoma is an epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli.

The differential diagnosis histologically includes rhabdomyosarcoma, granular cell tumor, alveolar soft part sarcoma, hibernoma, oncocytoma, and crystal storing histiocytosis, among others.

The molecular genetic defects in renal tumors of people with BHD are different from two other similar kidney tumors, chromophobe renal cell carcinoma and renal oncocytoma.

Renal tumors can manifest as multiple types of renal cell carcinoma, but certain pathological subtypes (including chromophobe, oncocytoma, and oncocytic hybrid tumors) are more commonly seen in BHD.

People with Birt-Hogg-Dubé syndrome also have an increased risk of developing cancerous or noncancerous kidney tumors (chromophobe renal cell carcinoma and oncocytoma, respectively) and possibly tumors in other organs and tissues.

The main differential diagnosis of renal oncocytoma is chromophobe renal cell carcinoma oncocytic variant, which like the renal oncocytoma has eosinophilic cytoplasm, but has perinuclear clearing and, typically, some degree of nuclear atypia.