pericyte
pericapillary cell
perivascular cell

These types of pericyte can also phagocytose exogenous proteins.

This occurrence causes pericyte deficiency around the vessels, leading to a defect in maturation.

This is important for pericyte differentiation.

Paracrine activity and oxygen availability have been shown to also modulate pericyte activity.

The stria vascularis also contains pericyte, melanocyte, and endothelial cells.

Experiments have demonstrated that oxygen levels also alter pericyte contraction and subsequent blood vessel contraction.

This destabilizes the endothelial cells, which accounts for less endothelial cell and pericyte interaction.

Sphingosine-1-phosphate (S1P) signaling also aides in pericyte recruitment by communication through G protein-coupled receptors.

Hyperglycemia-induced intramural pericyte death and thickening of the basement membrane lead to incompetence of the vascular walls.

A role for VEGF as a negative regulator of pericyte function and vessel maturation.

Furthermore, the elasticity of pericyte is beneficial because they can expand to reduce inflammation and allow harmful substances to diffuse out of the brain.

Aminopeptidase A also may be involved in pericyte recruitment due to its increased expression by activated pericytes in various pathological conditions associated with angiogenesis.

Because of their crucial role in maintaining and regulating endothelial cell structure and blood flow, abnormalities in pericyte function are seen in many pathologies.

Inhibition of subtype A pericyte generation caused improper closing of spinal cord incisions, which supports the idea that pericytes are important for scarring.

Similar to the inhibition of the PDGF pathway, angiopoietin 2 reduces levels of pericyte, leading to diabetic retinopathy.

Pericyte functionality (or dysfunctionality) is also theorized to contribute to neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS (Lou Gehrig's Disease).

These two types of cells can be easily distinguished from one another based on the presence of the prominent round nucleus of the pericyte compared to the flat elongated nucleus of the endothelial cells.

Contacts between adult SVZ neuronal precursors and blood vessels are unusually permeable and frequently devoid of astrocyte and pericyte interferences, suggesting that blood-derived cues are gaining direct access to adult neural precursors and their progeny.

A perivascular cell is in the periphery of vasculature, and may refer to:

Like perivascular cells, they express MHC class II proteins even at low levels of inflammatory cytokine activity.

Unlike perivascular cells, but similar to resident microglia, juxtavascular microglia do not exhibit rapid turnover or replacement with myeloid precursor cells on a regular basis.

Co-culturing 3T3-L1 pre-adipocytes in 3D with murine endothelial bEND.3 cells creates a vascular-like network assembly with concomitant lipogenesis in perivascular cells.

In regards to his discovery of "Kupffer cells" in 1876, he initially suggested that this type of cell belonged to a group of perivascular cells of the connective tissues or to the adventitial cells (pericytes).

The population of activated microglia at the site of a CNS injury includes not only endogenous microglia of the CNS but also exogeneous perivascular cells originating in the bone marrow that immigrate to the area and transform into microglia to supplement the microgliosis response.