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Sex steroid production may be sufficient to allow for normal sexual development as well and even fertility.
Certain pesticides are able to disturb the sex steroid hormone system and to act as antiandrogens.
The sex steroid deficiency produces effects similar to 17α-hydroxylase deficiency.
As sex steroid levels rise during puberty, bone maturation accelerates.
It is also responsive to changes in the levels of sex steroid hormone in the female reproductive tract.
Indeed, there is no information whatsoever on how any sex steroid affects Stx responsiveness of any cell type.
The association of excessive sex steroid effects with diseases of the adrenal cortex have been recognized for over a century.
The dual activities mediate three key transformations in cortisol and sex steroid synthesis:
Testosterone is an androgen sex steroid hormone.
That is, in the beginning, 17,20-lyase deficiency will block synthesis of sex steroid hormones, forcing the pathways to produce more cortisol.
Prostate growth and differentiation are highly dependent on sex steroid hormones, particularly DHT.
Mice have been used as an experimental system to investigate possible mechanisms by which levels of sex steroid hormones might regulate nervous system function.
Central precocious puberty can be treated by suppressing the pituitary hormones that induce sex steroid production.
Additional data relative to maternal ovaries and jugular plasma sex steroid hormone determinations are compiled in Table 3.
The drug that Jackson allegedly took - cyproterone acetate - like all anti-androgen drugs simply suppresses sex steroid hormones.
Gonadotropin and sex steroid levels fall to low levels (nearly undetectable by current clinical assays) for approximately another 8 to 10 years of childhood.
He became a pioneer in the description of intracellular sex steroid receptors and identified major intracellular participants such as the heat shock proteins.
Sex steroid (androgen, estrogen, and progestogen)
An advanced bone age is common when a child has had prolonged elevation of sex steroid levels, as in precocious puberty or congenital adrenal hyperplasia.
The pituitary extract contains gonadotropic hormones which stimulate gonad maturation and sex steroid production, ultimately promoting reproduction.
For example, male Zebra Finches castrated or given sex steroid inhibitors as hatchlings still develop normal masculine singing behavior.
Atrophy of the testes occurs with prolonged use of enough exogenous sex steroid (either androgen or estrogen) to reduce gonadotropin secretion.
Because the enzyme defect does not affect sex steroid synthesis, gonadal function at puberty and long-term fertility should be normal if adrenal androgen production is controlled.
We tested single nucleotide polymorphisms in 68 candidate genes in three functional groups (sex steroid synthesis/transport, neural connectivity, and social-emotional responsivity) in two experiments.