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He was the first Great Khan from the Toluid line, and made significant reforms to improve the administration of the Empire during his reign.
Möngke dispatched him to establish a firm Toluid control over the Middle East, and ordered him return to Mongolia when his task was accomplished.
When the Toluid family overthrew the Ögedeids, Qara Hulagu supported Möngke Khan in 1251.
After his death, descendants of Mukhali served the Great Khan of the Mongols, especially those of the Toluid lineage.
When, after the Toluid Möngke Khan's death, the Mongol Empire disintegrated into civil war, the members of the House of Ogedei were influential players in the politics of the region.
Retainers of the Toluid Hulagu participated in the conquest of Persia, then called Mollai, and later founded the Jalayirid Dynasty which ruled from Baghdad after the collapse of the Hulaguid Ilkhanate.