Should Hampton leave, it would be a huge blow to the team.
To lose three players in the first half was a huge blow.
The holding in this case was a huge blow to the fight for Indian sovereign.
The crash was a huge blow to the Russian military.
It was a huge blow to the city, too.
Reagan's decision was a huge blow to the power of unions.
The win was seen as a huge blow to the insurance industry.
A huge blow, they said, came last fall when she called her father for help paying a dental bill.
If Cross goes down, it would be a huge blow to the team.
They need to raise £20,000 or they'll have to close and that will be a huge blow for the parents.