In the 19th century, it was an important trade route.

This river used to be an important trade route in old days.

It is a more important route, usually a main line.

It is an important route for the people of the region.

The river was an important route in the days of the fur trade.

It is considered one of the most important historical routes in the state.

The city's position on an important trade route gave it a varied population for much of its history.

The role of the city was determined by its proximity to an important trade route.

The large scale of these accidents can close important routes for several days.

The area was an important trade route between Tenochtitlan and points south.